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Research: Critical Need

Millions of people have died throughout history from what was believed to be at the time an incurable disease.  The Bubonic Plague, an infection of the lymphatic system, claimed an estimated 200 million lives over several centuries before antibiotics were introduced in modern times.  Smallpox is a virus unique to humans that killed 60 million Europeans and decimated the Native American population by more than 10 million.  To this day, smallpox is the only human infectious disease known to have been completely eradicated.

The key to curing and treating these and dozens of other diseases and conditions is research.  Scientists believe that unlocking the mysteries of the stem cell could help untold millions who fall victim to various diseases, injuries and conditions.  

Here is a brief list of diseases and conditions (with some additional detail) already being helped through adult stem cell research and/or therapies.

Cerebral palsy, a condition where the brain is unable to control the muscles of the body, impacts as many as 10,000 newborns each each, accoording to the Center for Disease Control (CDC).  An experimental procedure at Duke University in North Carolina is being used with great success to treat this condition.  Children with cerebral palsy are being infused with their own cord blood stem cells to heal and repair damaged brain tissue.  

Parkinson’s Disease, attacks the nervous system of the human body, and is caused by a slow, almost imperceptible loss of cells in the brain that produce a chemical necessary for muscles to work normally.  Many people have come to know the main symptom of Parkinson’s as the disease that causes uncontrollable shaking of the hands, arms or legs.  After Alzheimer's disease, Parkinson's Disease is the most common neurodegenerative disorder, with an estimated lifetime risk of approximately 1 in 100 persons. It is most common in men and women over 50.

Leukemia is defined by the National Cancer Institute as a “Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.”  Nearly 45,000 new cases are diagnosed each year with more than 20,000 dying from leukemia annually in the United States.

Multiple Sclerosis (MS) is a disease that has been called “the crippler of young adults", normally affecting people under 45 years-old, impacting each victim a little differently.  It can cause blurred or otherwise impaired vision, the loss of muscular strength, poor balance, “tingling” throughout parts of the body bladder control problems, memory lapses and much more.  2.5 million people, including 400,000 Americans are affected by MS, 70% of MS victims are women.

Here is a more complete list of diseases and conditions that are being helped by adult stem cell research and/or therapies.

CANCERS:

Brain Cancer

Retinoblastoma

Ovarian Cancer

Skin Cancer: Merkel Cell Carcinoma

Testicular Cancer

Tumors abdominal organs Lymphoma

Non-Hodgkin’s lymphoma

Hodgkin’s Lymphoma

Acute Lymphoblastic Leukemia

Acute Myelogenous Leukemia

Chronic Myelogenous Leukemia

Juvenile Myelomonocytic Leukemia

Chronic Myelomonocytic Leukemia

Cancer of the lymph nodes: Angioimmunoblastic Lymphadenopathy

Multiple Myeloma

Myelodysplasia

Breast Cancer

Neuroblastoma

Renal Cell Carcinoma

Various Solid Tumors

Soft Tissue Sarcoma

Ewing’s Sarcoma

Waldenstrom’s macroglobulinemia

Hemophagocytic lymphohistiocytosis

POEMS syndrome

Myelofibrosis


AUTO-IMMUNE DISEASES:

Diabetes Type I (Juvenile)

Systemic Lupus

Sjogren’s Syndrome

Myasthenia

Autoimmune Cytopenia

Scleromyxedema

Scleroderma

Crohn’s Disease

Behcet’s Disease

Rheumatoid Arthritis

Juvenile Arthritis

Multiple Sclerosis

Polychondritis

Systemic Vasculitis

Alopecia Universalis

Buerger’s Disease


CARDIOVASCULAR:

Acute Heart Damage

Chronic Coronary Artery Disease


OCULAR:

Corneal regeneration


IMMUNODEFICIENCIES:

Severe Combined Immunodeficiency Syndrome

X-linked Lymphoproliferative Syndrome

X-linked Hyper immunoglobulin M Syndrome


NEURAL DEGENERATIVE DISEASES AND INJURIES:

Parkinson’s Disease

Spinal Cord Injury

Stroke Damage


ANEMIAS AND OTHER BLOOD CONDITIONS:

Sickle Cell Anemia

Sideroblastic Anemia

Aplastic Anemia

Red Cell Aplasia

Amegakaryocytic Thrombocytopenia

Thalassemia

Primary Amyloidosis

Diamond Blackfan Anemia

Fanconi’s Anemia

Chronic Epstein-Barr Infection


WOUNDS AND INJURIES:

Limb Gangrene


Surface Wound Healing

Jawbone Replacement

Skull Bone Repair

 

OTHER METABOLIC DISORDERS:

Hurler’s Syndrome

Osteogenesis Imperfecta

Krabbe Leukodystrophy

Osteopetrosis

Cerebral X-Linked Adrenoleukodystrophy


LIVER DISEASE:

Chronic Liver Failure

Liver Cirrhosis


BLADDER DISEASE:

End-Stage Bladder Disease